Any gun can and will kaboom if treated incorrectly.
Here is a link to a KB of a Colt Anaconda, which is a very strongly and well made .44 Magnum revolver. Which has a fully supported chamber.
The issue as I see it, stems mainly from reloaded ammunition and unsupported chambers.
With reloaded ammunition, you should ALWAYS examine EVERY case for signs of stress.
You also need to be VERY carefull when reloading to not overcharge a cartridge, or seat a bullet too far, or crimp a cartridge that is not supposed to be crimped, or undercharge a cartridge so it causes a squib, or...
I don't use (or recommend) reloaded ammunition, even commercially reloaded ammunition, in any firearm with an unsupported chamber. Doing so is asking for a KB in my opinion.
I personally won't use reloaded ammunition that I wasn't involved in the reloading of. Your eyes and hands may be worth saving a few dollars on ammunition, but mine are more important to me.