Yeah, it's something you can do yourself, but you'll need to use locktite for the frontsight. -It'll be down for 24 hours as the locktite sets.
The tools you'll need are a radiused screwdriver for the screw in the rearsight. You'll need a 3/16 hex for the frontsight. Be careful with the locktite you want the one that can be undone by pressure not heat. At some point the night sights will wear out and need to be replaced (6-8 years for Mepro's). You don't want to need to heat it while it is mounted to the slide.
-It's not that difficult, but it is easy to mess up. When some people pull off the the rearsight, they lose the "spring loaded" detent. When you slide off the rearsight, be careful. Do it slowly and be ready to put your thumb over it so it doesn't fly. Take the screw out from the rearsight and install it in the Mepro. -Also be careful to get the 3/16 hex screwed in straight and not off at an angle.
Good luck