There is a pistol range in lower Manhattan that is frequented by various members of the Israeli embassy and consular staff...not just security personnel. but clerks, cooks, maintenance, etc. Many of them will carry small/compact .22 LR semi-auto pistols for personal protection (Walther PP, Beretta Bobcat, etc), . Many of them work long and hard to become VERY proficient at marksmanship...obliterating a 1" bullseye with 7 or 8 rounds from a .22 magazine at 25 yards...in only a few seconds of rapid fire. .22 bullets may be small but...put enough of 'em in the same spot and they'll do a whole lotta' damage..
The '...catch..' is that ya' gotta' spend a whole lotta' time and effort gettin' that good...and then be tested on your marksmanship proficiency on a regular basis....something that relatively FEW civilians are willing to take the time or make the effort to do. Goin' out to the range every few/several months or so and shootin' a couple of boxes of ammo and punchin' holes in a Diet Pepsi can ain't gonna' do it.So, NO. A .22 pistol really ain't an adequate concealed carry weapon for most people...no matter how creative a manufacturer's catalog marketing staffer wants to be.